Transplantation of fetal tissues

Isolation of mesenchymal stem cells from fetal tissues

Backgrond&Objective: The ability of mesenchymalstem cells (MSCs) differentiation into many cell types, as well as their ex vivo expansion potential, makes them as an attractive therapeutic tool for cell transplantation and tissue engineering. This project was designed to improve isolation culture and characterization of human amniotic membran-derivedMSSCS and human warton ,s jelly- derived MSCs...

Fetal Liver Transplantation

and allogeneic cells, sequentially. Chimerism was defined by chromosomal analysis and HLA typing. in which ene haplotype seemed to be shared betwecn the donor and the host by chance. However, defective irnrnunoglobulin productien has not yet been cerrected, The assay on T-B lymphocyte intcraction in ndtre suggested that the/ failure might be attributed to an intrinsic dafect of B lymphocytes, w...

Fetal hyperinsulinemia increases farnesylation of p21 Ras in fetal tissues.

Even though the role of fetal hyperinsulinemia in the pathogenesis of fetal macrosomia in patients with overt diabetes and gestational diabetes mellitus seems plausible, the molecular mechanisms of action of hyperinsulinemia remain largely enigmatic. Recent indications that hyperinsulinemia "primes" various tissues to the mitogenic influence of growth factors by increasing the pool of prenylate...

Fetal tissue research: legal regulation of human fetal tissue transplantation.

Transplantation and Potential Immortality of Mammalian Tissues

1. Serial transplantation of tumors made it possible in 1901 and following years to draw the conclusion that various mammalian tissues have potential immortality. Serial transplantations of normal tissues did not succeed at first, because the homoioreaction on the part of the lymphocytes and connective tissue of the host injures the transplant. 2. In continuation of these experiments we found t...